
Weight Loss Medications: Simple Comparison
Overview of how semaglutide, tirzepatide, and phentermine work in simple terms.
1. Semaglutide
Type: Hormone-based (GLP-1 receptor agonist). Mimics natural fullness hormones. Helps you feel full faster, slows digestion, and reduces appetite.
2. Tirzepatide (Mounjaro)
Type: Hormone-based (dual GIP + GLP-1). Works like semaglutide but stronger by targeting two hormones. Helps increase fullness and improve blood sugar control.
3. Phentermine
Type: Stimulant (sympathomimetic). Works on the nervous system to reduce hunger and increase alertness. Acts more like a stimulant rather than a hormone.
Key Differences
| Medication | Type | How it Works |
|---|---|---|
| Semaglutide | Hormone-based | Mimics fullness signals |
| Tirzepatide | Hormone-based (dual) | Stronger fullness + metabolism effects |
| Phentermine | Stimulant | Suppresses appetite via brain stimulation |